Most commercial hand sanitizers are formulated with 70% ethanol or isopropanol (IPA), combined with stabilizing ingredients such as glycerol and 1–2% hydrogen peroxide. While effective for microbial control, this chemistry can unintentionally generate harmful by‑products.
When ethanol and hydrogen peroxide are used together, they can produce up to 1000 ppm of acetaldehyde, a regulated volatile organic compound. Hydrogen peroxide can also react with organic components in the sanitizer, oxidizing alcohols into formaldehyde, another compound associated with health risks and strict regulatory limits.
Why Aldehyde Testing Matters
The accumulation of formaldehyde and acetaldehyde in hand sanitizers poses potential health concerns, especially for front‑line workers, healthcare staff, and frequent users. Reliable testing is essential for manufacturers aiming to meet safety standards, maintain product quality, and protect end‑users from unnecessary exposure. LCS Laboratory specializes in detecting and quantifying trace aldehydes in sanitizer formulations. Our analytical services help manufacturers verify compliance, troubleshoot formulation issues, and ensure their products remain safe throughout their shelf life.
Our Analytical Method: High‑Accuracy Aldehyde Detection
LCS Laboratory uses a high‑precision HPLC‑UV analytical method designed specifically for aldehyde determination. The workflow includes:
- Catalytic neutralization of hydrogen peroxide to eliminate analytical interference
- Derivatization with 2,4‑dinitrophenylhydrazine (DNPH) to enhance sensitivity and stability of aldehyde detection
- Alignment with NIOSH Methods 2016 and 2018, ensuring defensible, industry‑recognized results
This method delivers accurate, reproducible quantification of formaldehyde and acetaldehyde, even at very low concentrations.
Air Quality Testing for Worker Protection
Beyond product testing, LCS Laboratory also provides comprehensive air quality analysis for alcohols, formaldehyde, and acetaldehyde. These services support industrial hygiene consultants, safety professionals, and employers in assessing occupational exposure and maintaining safe working environments. If you’d like to discuss your testing needs or require technical guidance, feel free to reach out. Our team is ready to support your project with the scientific expertise and analytical precision you expect. ©
